Parpati Kalpa : A Pharmaceutical Dosage Form

Description

Parpati Kalpa Ayurveda is the only science which not only given the due importance to all the states of duug but also exploited them by utilizing all parts including the ashes. It is the earliest science which has given full freedom to design and develop wide variety of dosage forms depending on the requirement of the condition of the patient and the disease demands, by saying what ever the number of drug preparations mentioned in the classics are only small. It further has laid down so many guidelines for the design and develop the newer drug entities. Though the classical samhitas have made use of minerals and metals in the treatment but they concentrated more on herbal ingredients and less on minerals. These samhitas have documented a number of dosage forms specially herbal drugs based on five fundamental forms viz panchavidha kashaya kalpanas in their individual and compound forms.

In succession to this, they have invented newer dosage forms, taking so many factors like the palatability, aesthetics, shelf life and kinetics etc into consideration. However, these formulations are revolved mostly around the herbals only. This trend was revolutionized with the evolving of Rusa Shastra a specialized branch which explicitly exploited metals and minerals in the therapeutics taking the advantage of their requirement at micron levels, freedom from palatability problems and more over to all of these the instantaneous relief to the patient from the ailment. In this process the scholars of Rasa shastra have developed innumerable formulations in various flawless awesome dosage forms. Among them the Parpati is one of the dosage form. Though it is specially designed to treat the Grahanisprue syndrome like conditions but still it is indicated in variety ol’ disease conditions which also addressed the gynaecological problems. Who has designed and developed this dosage form is a big controversial issue but this dosage form has proved its potential wherever and whatever condition it has been tried.

As such this form comprises a fusion material to which all other active ingredients whether theymay be herbal or animal or mineral nature will be added after bringing into molten state over mild heat and sandwiched the molten mixture in between the plant leaves preferably the plantain leaf using cow dung as cooling medium so as to convert the molten mixture into thin wafers. Simply by melting the material over mild heat and sandwich to make wafers will bring about a dramatic change in its pharmacological action. Initially the material specifically if contains Mercury and Sulphur, it processes catharetic action whereas when the same material is converted to Parpati it acts as bowel binder. Simple heat treatment and sandwiching has bring about this remarkable change. Not only this dosage form has another distinction is that the dosage and method of administration. It is Just like some of the modern drugs has to be administered in increasing fashion and maintain after reaching optimum dosage level and then onwards tapering the dose instead of cutting off the dose all of a sudden so as to bring the drug levels in blood and other tissues and its effect to baseline slowly.

In fact, aeach of the dosage form mentioned in Rasa Shastra has distinct method of administration as well as dosage. Keeping this distinct, selective and spec, ialness attached with this dosage form it has attracted our attention to compile all the formulae which involve the manufacturing process of Parpati and bring out as a book. In this Endeavour we have gone through a number of books and the compilation works on formulary and tried all such formulae and presented in a systematic pattern. We feel that the book will help not only all the Ayurvedic fraternity but also help the modern scientific community in and abroad. With Deep regrets and sorrow I lay my profound respect, regard and love to my Better Half who had deserted me during the journe, of writing this book and left to her heavenly abode.